Programme scientifique

Programme et ateliers pré-congrès

SATURDAY, SEPTEMBER 20 08:30
18:30
Pre-congress tutorials
SUNDAY, SEPTEMBER 21 08:30
12:30
Pre-congress tutorials
13:00
16:00
Registration
17:30
19:00
Opening address
  • Honorary Presidents
  • Local authorities
19:00
19:45
Opening conference
  • J. K. Frenkel
    • Proof of the Identity of the New Oocyst and Toxoplasma Infectivity in 1970
  • W. de Souza
    • Brazilian contribution for a better knowledge on the biology of Toxoplasma gondii
19:50
20:05
Video exhibition
  • A. Mérieux - 100 years of fight
20:05
21:05
Honours session
  • Elmer Pfefferkorn
  • Georges Desmonts
  • Jack K. Frenkel
  • Jack S. Remington
  • Jitender P. Dubey
  • Mário Endzfeld Camargo
  • Pierre Ambroise-Thomas
21:15
22:30
Welcome reception
MONDAY, SEPTEMBER 22 08:00
08:30
Plenary session 1

Chairpersons: J. K. Frenkel and F. Derouin

  • Conference: Toxoplasma gondii from 1908 to 2008 - Homage to Nicolle, Manceaux and Splendore
    • D. Ferguson
08:30
09:45
Plenary session 2 : Genetic variation and its role in disease outcome
Chairpersons: S. Gennari and M-F. Cesbron
  • Conference (20 min): Population biology of T. gondii strains. What’s out there and where did they come from?
    • J. P. Dubey
  • Conference (20 min): Influence of parasite genotype on clinical manifestations
    • D. Ajzenberg
  • Conference (20 min): Human genetic markers and clinical manifestations in humans
    • J. Blackwell
09:45
10:00
Coffee break
10:00
11:45
Plenary session 3: Genes and proteins responsible for genetic variation and its role in disease outcome
Chairpersons: J. P. Dubey and W. Sullivan
  • Conference (20 min): Identifying parasite genes and proteins influencing disease outcome
    • D. Sibley
  • Conference (20 min): Introducing proteins into the host cell
    • J. F. Dubremetz
  • Conference (20 min): Mechanisms of molecular cross-talk with host cell
    • J. Boothroyd
  • Conference (2 x15 min): Regulating gene expression
    • A. Hakimi / K. Kim
12:00
14:00
Lunch
14:00
14:50
Plenary session 4: Genome organization, differentiation and pathogenesis
Chairpersons: D. Sibley and J. Blackwell
  • Conference (20 min): Understanding genome organization and microarray analysis of expression and genotype
    • D. Roos
  • Conference (20 min): Understanding mechanisms and role of differentiation in pathogenesis
    • W. Sullivan
14:50
16:20
Plenary session of selected presentations 1 (7 x 10 min):
Chairpersons: M. Grigg and M. Attias
(Please see “Selected Presentations” page for further details)
  • Molecular epidemiology
  • Gene expression and regulation
  • Cell biology
16:25
16:40
Coffee break
16:45
17:55
FORUM 1: Genetics and pathogenesis
Moderator: J. Boothroyd

Special Poster Presentations - 4 x 5 min:
  • Role of glycosylphosphatidylinositols in the pathogenicity of apicomplexan parasites
    (N. Azzouz, F. Kamena, B. Lepenies, M. Treeck, T. W. Gilberger, P. H. Seeberger)
  • Interaction and cystogenesis of Toxoplasma gondii within the skeletal muscle cells in vitro
    (E.V. Guimarães, L. Carvalho, H.S. Barbosa)
  • Serotyping of Toxoplasma gondii: striking homogeneous pattern between symptomatic and asymptomatic infections within Europe and South America
    (F. Peyron, S. Morisset, J. Lobry, J. Garweg, E. Petersen, V. Meroni, J. E. Gomez-Marin, A. de-la-Torre, B. Carme, J. F. Garin, M-F. Cesbron)
  • Genetic characterization of Toxoplasma gondii isolates from China
    (P. Zhou, H. Zhang, R.Q. Lin, H.Q. Song, C. Su, X.Q. Zhu)
Open debate:
  • How can the influence of strain type be of use clinically?
  • What do the clinicians need from the basic scientists and vice versa?
  • What data need to be acquired and from what group of patients?
  • Does Toxoplasma disseminate through the body inside cells or extracellularly?

Pannellists: M-L. Dardé, D. Sibley, M. Grigg, A. Barragan, C. Carvalheiro and F. Peyron

18:00
19:30
Poster session 1 (authors present at the poster)
(Please see “Poster Session” pages for further details)
19:30
21:00
Entertainment
20:30
22:00
Dinner (bioMérieux Presidential Dinner)
TUESDAY, SEPTEMBER 23 08:30
10:15
Plenary session 5: Host response
Chairpersons: O. Liesenfeld and A. kijlstra
  • Conference (20 min): Immunology of T. gondii infection in the immunocompetent host
    • C. Hunter
  • Conference (20 min): NK cells, dendritic cell, mucosal immunity
    • Buzoni-Gatel
  • Conference (20 min): Host factors and the gut flora impact outcome of oral infection with Toxoplasma gondii
    • O. Liesenfeld
  • Conference (20 min): New developments in vaccines against T. gondii
    • E. Innes
  • Conference (20 min): Toxoplasma gondii, CD40 and autophagy
    • C. Subauste
10:15
10:35
Coffee break
10.40
12:25
Plenary session 6: Ocular toxoplasmosis
  • Conference (20 min): New findings on physiopathology of ocular toxoplasmosis
    • R. Belfort
  • Conference (20 min): Treating ocular toxoplasmosis - current evidence
    • M. Stanford
Debate:
Moderator: C. Silveira and A. Brézin
Management of Toxoplasma eye disease – different approaches in Europe (M. Stanford, A. Brezin) and South
America (C. Silveira, R. Belfort, or C. Muccioli, L.V. Rizzo, J. Melamed)
12.30
13:30
Diasorin Lunch Symposium (open to all the congress delegates)

Screening for toxoplasmosis During Pregnancy: a French, Italian and Brazilian Perspective
President: A. W. Ferreira. Speakers: F. Peyron, V. Meroni and E. G. Lago
Chairpersons: R. McLeod and V. Chioccola

13.45
14:35
Plenary session 7: Metabolism, Cell biology and drug targets
Chairpersons: F. Derouin and R. Vommaro
  • Conference (20 min): Systematic analysis of vesicle trafficking in Apicomplexan parasites
    • M. Meissner
  • Conference (20 min): What new metabolism findings could bring to therapeutics?
    • E. Maréchal
14.35
16:05
Plenary session of selected presentations 2 (7 x 10 min):
Chairpersons: R. McLeod and V. Chioccola
(Please see “Selected Presentations” page for further details)
  • Immunology
  • Cell biology
  • Metabolism
  • New drugs
  • Ocular toxoplasmosis
16:05
16:25
Coffee break
16:30
17:30
FORUM 2: Critical points in vaccine development
Introducing expert conference and moderator: E. Petersen, E. Jongert and A. Arnholdt

Special Poster Presentations - 2 x 5 min:
  • A GRA1-GRA7 cocktail DNA vaccine primes anti-Toxoplasma immune responses in mice and pigs
    (E. Jongert, V. Melkebeek, S. De Craeye, D. Verhelst, E. Cox)
  • Ribosomal protein S13 conditional knockout parasite protects mice from toxoplasmosis
    (R. McLeod, S. Hutson, E. Mui, B. Rohrman, W. Witola, N. von Poppel, R. Schaap)
Open debate:
  • Why do attenuated strains provide protection and not subunit and plasmid vaccines?
  • What is the role of adjuvants? Should we focus more on adjuvants compared to selecting antigens?
  • What is an appropriate endpoint? Reduction in eye symptoms, prevention of transmission freedom of tissue cysts in the immunized host?
  • Do we need to test vaccines for protection against different T. gondii genotypes?
17:30
19:30
Poster session 2 (authors present at the poster)
(Please see “Poster Sessions” pages for further details)
20:00
21:15
Entertainment
WEDNESDAY, SEPTEMBER 24 08:30
10:25
Plenary session 8: Evaluating treatment of congenital toxoplasmosis effectiveness across continents
Chairpersons: E. Petersen and C. Carvalheiro
  • Conference (2 x 15 min): Long term follow-up of children in
    • Europe (F. Peyron) and
    • USA (R. McLeod)
  • Conference (15 min): Cohort of congenital toxoplasmosis in South America
    • J. Gomez-Marin
  • Conference (20 min): Critical review of treatment efficacy for congenital toxoplasmosis
    • R. Gilbert
  • Conference (20 min): Options for clinical trials for treatment of ocular and congenital toxoplasmosis
    • G. Chêne
10:30
10:45
Coffee break
10:45
13:00
Plenary session 9: Environment, animal, and food
Chairpersons: M-L. Dardé and S. Carnevalle
  • Conference (20 min): Oocyst wall formation and composition in coccidian parasites
    • N. Smith
  • Video link with Dartmouth Medical School , New Hampshire, USA (10 minutes): “Greetings to Elmer Pfefferkorn
  • Conference (10 min): Detection of Toxoplasma gondii in water: proposition of a strategy and evaluation in Champagne-Ardenne region
    • I. Villena
  • Conference (10 min): Environmental research on toxoplasmosis: where can it take us?
    • L. Bahia-Oliveira
  • Conference (10 min): T. gondii in animal used for human consumption
    • A. Tenter
  • Conference (10 min): Risk assessment for food borne toxoplasmosis
    • F. Derouin
  • Conference (10 min): Disease burden in DALY’s
    • L. M. Kortbeek
* Lunch will be served during this session
13:40
14:30
Poster session 3 (authors present at the poster)
(Please see “Poster Sessions” pages for further details)
14:35
16:05
Plenary session of selected presentations 3 (7 x 10 min):
Chairpersons: O. Djurkovic and W. Buffolano
(Please see “Selected Presentations” page for further details)
  • Diagnosis and treatment
  • Environment
Satellite symposium: Toxoplasma databases and biological resources - Online session
  • Toxo DB
    • D. Roos
  • Biological Resource Center Toxoplasma
    • M-L. Dardé
  • Other experiences
    • D. Sibley
Debate: How to improve and manage T. gondii resources
16:05
16:25
Coffee break
16:30
18:00
FORUM 3: Diagnosis, follow-up and screening; Disease burden
Introducing expert conference: Breakthrough in diagnosis: H. Pelloux

Open debate on screening and follow-up (neonatal, prenatal, immunocompromised), disease burden:

Women screening: how and when? Which methods are recommended? How to evaluate the disease burden? How to diagnose at birth? How long and how should babies be followed-up? How to diagnose and follow-up ocular toxoplasmosis?

Panelists: R. McLeod, E. Camargo Neto, I. Villena

Who, how and when to screen immunocompromised patients? What for? Which methods are recommended? Respective values of PCR and serology?

Panelists: V. Meroni, E. Petersen, F. Derouin
18:00
19:00
Round Table: Meeting Evaluation and Perspectives
Chairpersons: L. Bahia-Oliveira and F. Derouin

J. Boothroyd, E. Petersen, H. Pelloux, M-L. Dardé, C. Carvalheiro
20:00
22:00
Brazilian barbecue

print this page Imprimer cette page